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NitroCure™ Treatment Instructions
1. Dip Treatment (Individual Fish)
Purpose: Rapid, high-concentration exposure for severe localized infections (ulcers, fin rot, mouth rot).
Duration: 15–20 minutes.Dosage: 100–300 mg/L (≈ 0.38–1.13 g per gallon).
Example: 5 gallons of dip water → 2–6 g NitroCure.- Fill a clean container with fresh, dechlorinated pond water.
- Add the correct amount of NitroCure and stir until dissolved.
- Place the koi in the dip for 15–20 minutes, observing closely.
- Provide aeration during treatment.
- Remove fish immediately if signs of stress occur.
- Return koi to the main pond or recovery tank.
2. Short-Term Bath Treatment
Purpose: Broader antibacterial exposure for several fish or moderate infections.
Duration: 6–8 hours.Dosage: 25 g per 1,000 gallons (≈ 6.6 mg/L).
Examples: 250 gallons → 6.25 g | 1,000 gallons → 25 g- Pre-dissolve NitroCure in a bucket of warm pond water.
- Add evenly across the treatment tank or pond.
- Maintain strong aeration throughout.
- Leave fish in treatment water for 6–8 hours.
- Perform a 25–30% water change after treatment if practical.
3. Long-Term Bath Treatment
Purpose: Continuous, lower-dose exposure for systemic infections or pond-wide outbreaks.
Duration: 5–7 days (re-dose if water changes are made).Dosage: 19 g per 1,000 gallons (≈ 5 mg/L).
Examples: 1,000 gallons → 19 g | 5,000 gallons → 95 g- Mix the correct amount of NitroCure in a bucket of pond water.
- Distribute evenly around the pond.
- Keep filters and aeration running as normal.
- Avoid carbon or other chemical filtration during treatment.
- Observe fish daily for improvement.
- After 5–7 days, perform a 25–30% water change.
Quick Reference Dosage Table
Treatment Dosage Example Coverage Dip 100–300 mg/L
(0.38–1.13 g/gal)5 gal → 2–6 g Short-Term Bath 25 g / 1,000 gal
(6.6 mg/L)1,000 gal → 25 g Long-Term Bath 19 g / 1,000 gal
(5 mg/L)5,000 gal → 95 g -
Precautions & Safety Information
- Keep Out of Reach of Children: Store NitroCure™ in a secure location, away from children and pets.
- For Ornamental Fish Only: Not for use on fish intended for human consumption.
- Protective Gear: Wear gloves and avoid inhalation of powder when handling. Wash hands thoroughly after use.
- Storage: Store in a cool, dry place away from direct sunlight and moisture.
- Filtration: Do not use activated carbon or chemical filter media during treatment, as they will remove the medication.
- Water Quality: Ensure strong aeration and monitor ammonia, nitrite, and oxygen levels throughout treatment.
- Avoid Overdosing: Carefully measure NitroCure™ to prevent unnecessary stress or harm to fish.
- Disposal: Dispose of unused product and empty containers in accordance with local regulations.
Note: NitroCure™ is intended for use in koi ponds and ornamental water features only. Always follow dosage instructions carefully.
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Q: How do NitroCure™, KoiCure™, and KanaRx™ differ?
A: All three are pure Aqua Meds antibiotic treatments, but they are used at different stages:- NitroCure™ (nitrofurazone) – First-line external bath treatment for most ulcers, fin rot, tail rot, and gill disease. Can be used as a dip, short-term bath, or long-term bath.
- KoiCure™ (oxolinic acid) – Strong immersion treatment for more serious or persistent external infections, especially those with a gram-negative or septicemia appearance (red streaks, bloody patches).
- KanaRx™ (kanamycin sulfate) – Deep, broad-spectrum antibiotic for severe, resistant, or internal infections. Can be used as a bath, pond immersion, or medicated food.
We do not recommend using them at full strength at the same time. Instead, they can be used sequentially (for example: start with NitroCure, step up to KoiCure if needed, and reserve KanaRx for the most advanced cases or internal infections).
Q: Which one should I use first?
A: As a simple rule of thumb:- For new, straightforward external infections, start with NitroCure™.
- For more serious or persistent external infections, consider KoiCure™.
- For severe, resistant, or clearly internal infections, or when you need medicated food, use KanaRx™.
For a more detailed comparison and dosing overview, read our full guide:
NitroCure™ vs. KoiCure™ vs. KanaRx™: Which Aqua Meds Antibiotic Should I Use? - Is this the right Aqua Meds® product for my sick fish or pond water problem?
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